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GLE1 antibody (AA 1-300)
GLE1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GLE1 Antibody
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Target
See all GLE1 Antibodies
GLE1
(GLE1 RNA Export Mediator (GLE1))
Binding Specificity
All epitopes for GLE1 antibodies
AA 1-300
Reactivity
All reactivities for GLE1 antibodies
Human
Host
All hosts for GLE1 antibodies
Rabbit
Clonality
All clonalities for GLE1 antibodies
Polyclonal
Conjugate
All conjugates for GLE1 antibodies
This GLE1 antibody is un-conjugated
Application
All applications for GLE1 antibodies
Western Blotting (WB)
Sequence
MPSEGRCWET LKALRSSDKG RLCYYRDWLL RREDVLEECM SLPKLSSYSG WVVEHVLPHM QENQPLSETS PSSTSASALD QPSFVPKSPD ASSAFSPASP ATPNGTKGKD ESQHTESMVL QSSRGIKVEG CVRMYELVHR MKGTEGLRLW QEEQERKVQA LSEMASEQLK RFDEWKELKQ HKEFQDLREV MEKSSREALG HQEKLKAEHR HRAKILNLKL REAEQQRVKQ AEQERLRKEE GQIRLRALYA LQEEMLQLSQ QLDASEQHKA LLKVDLAAFQ TRGNQLCSLI SGIIRASSES
Cross-Reactivity
Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GLE1 (NP_001003722.1).
Isotype
IgG
Top Product
Discover our top product GLE1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:1000 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for GLE1
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Target
GLE1
(GLE1 RNA Export Mediator (GLE1))
Alternative Name
GLE1 (GLE1 Products )
Synonyms
Dmel\\CG14749 antibody, GLE1 antibody, GLE1L antibody, LCCS antibody, LCCS1 antibody, hGLE1 antibody, Gle1l antibody, 4933405K21Rik antibody, AA553313 antibody, CG14749 gene product from transcript CG14749-RA antibody, nucleoporin GLE1 antibody, RNA export factor Gle1 antibody, GLE1, RNA export mediator antibody, GLE1 RNA export mediator antibody, GLE1 RNA export mediator (yeast) antibody, CG14749 antibody, CpipJ_CPIJ014147 antibody, SJAG_03847 antibody, GLE1 antibody, Gle1 antibody
Background
This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GLE1,GLE1L,LCCS,LCCS1,hGLE1,Epigenetics & Nuclear Signaling,Signal Transduction,GLE1
Molecular Weight
75 kDa/79 kDa
Gene ID
2733
UniProt
Q53GS7
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