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GLE1 antibody (AA 1-300)

GLE1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6141121
  • Target See all GLE1 Antibodies
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300
    Reactivity
    • 16
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 14
    • 3
    Rabbit
    Clonality
    • 16
    • 1
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    This GLE1 antibody is un-conjugated
    Application
    • 12
    • 8
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MPSEGRCWET LKALRSSDKG RLCYYRDWLL RREDVLEECM SLPKLSSYSG WVVEHVLPHM QENQPLSETS PSSTSASALD QPSFVPKSPD ASSAFSPASP ATPNGTKGKD ESQHTESMVL QSSRGIKVEG CVRMYELVHR MKGTEGLRLW QEEQERKVQA LSEMASEQLK RFDEWKELKQ HKEFQDLREV MEKSSREALG HQEKLKAEHR HRAKILNLKL REAEQQRVKQ AEQERLRKEE GQIRLRALYA LQEEMLQLSQ QLDASEQHKA LLKVDLAAFQ TRGNQLCSLI SGIIRASSES
    Cross-Reactivity
    Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GLE1 (NP_001003722.1).
    Isotype
    IgG
    Top Product
    Discover our top product GLE1 Primary Antibody
  • Application Notes
    WB,1:1000 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Alternative Name
    GLE1 (GLE1 Products)
    Synonyms
    Dmel\\CG14749 antibody, GLE1 antibody, GLE1L antibody, LCCS antibody, LCCS1 antibody, hGLE1 antibody, Gle1l antibody, 4933405K21Rik antibody, AA553313 antibody, CG14749 gene product from transcript CG14749-RA antibody, nucleoporin GLE1 antibody, RNA export factor Gle1 antibody, GLE1, RNA export mediator antibody, GLE1 RNA export mediator antibody, GLE1 RNA export mediator (yeast) antibody, CG14749 antibody, CpipJ_CPIJ014147 antibody, SJAG_03847 antibody, GLE1 antibody, Gle1 antibody
    Background
    This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GLE1,GLE1L,LCCS,LCCS1,hGLE1,Epigenetics & Nuclear Signaling,Signal Transduction,GLE1
    Molecular Weight
    75 kDa/79 kDa
    Gene ID
    2733
    UniProt
    Q53GS7
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