GIP antibody (AA 22-153)

Catalog No. ABIN6141091

Product Details anti-GIP Antibody

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Binding Specificity: AA 22-153

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EKKEGHFSAL PSLPVGSHAK VSSPQPRGPR YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI TQREARALEL ASQANRKEEE AVEPQSSPAK NPSDEDLLRD LLIQELLACL LDQTNLCRLR SR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-153 of human GIP (NP_004114.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GIP

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Alternative Name: GIP (GIP Products)

Synonyms: GIP antibody, xgip antibody, Gludins antibody, RATGLUDINS antibody, gastric inhibitory polypeptide antibody, gastric inhibitory polypeptide L homeolog antibody, GIP antibody, gip antibody, Gip antibody, gip.L antibody

Background: This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.,GIP,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Growth factor,GIP

Molecular Weight: 17 kDa

Gene ID: 2695

UniProt: P09681

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism