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GGCX antibody (AA 479-758)

GGCX Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6141069
  • Target See all GGCX Antibodies
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    Binding Specificity
    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 479-758
    Reactivity
    • 34
    • 22
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 1
    • 1
    Rabbit
    Clonality
    • 49
    Polyclonal
    Conjugate
    • 14
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GGCX antibody is un-conjugated
    Application
    • 25
    • 23
    • 19
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    QRIFDPRVDI VQAAWSPFQR TSWVQPLLMD LSPWRAKLQE IKSSLDNHTE VVFIADFPGL HLENFVSEDL GNTSIQLLQG EVTVELVAEQ KNQTLREGEK MQLPAGEYHK VYTTSPSPSC YMYVYVNTTE LALEQDLAYL QELKEKVENG SETGPLPPEL QPLLEGEVKG GPEPTPLVQT FLRRQQRLQE IERRRNTPFH ERFFRFLLRK LYVFRRSFLM TCISLRNLIL GRPSLEQLAQ EVTYANLRPF EAVGELNPSN TDSSHSNPPE SNPDPVHSEF
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 479-758 of human GGCX (NP_000812.2).
    Isotype
    IgG
    Top Product
    Discover our top product GGCX Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    Alternative Name
    GGCX (GGCX Products)
    Synonyms
    GGCX antibody, cb751 antibody, si:ch1073-230p18.3 antibody, zgc:158736 antibody, ggcx antibody, GGC antibody, vkcfd1 antibody, CG13927 antibody, DgammaC antibody, Dmel\\CG13927 antibody, dGC antibody, dgammaC antibody, gammaC antibody, VKCFD1 antibody, gamma-glutamyl carboxylase antibody, gamma-glutamyl carboxylase L homeolog antibody, GGCX antibody, ggcx antibody, GC antibody, sce5891 antibody, ggcx.L antibody, Ggcx antibody
    Background
    This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants.,GGCX,VKCFD1,Cardiovascular,Blood,Coagulation,GGCX
    Molecular Weight
    80 kDa/87 kDa
    Gene ID
    2677
    UniProt
    P38435
    Pathways
    SARS-CoV-2 Protein Interactome
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