GARS antibody (AA 60-370)

Catalog No. ABIN6140964

Product Details anti-GARS Antibody

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Binding Specificity: AA 60-370

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: AEEVLAPLRL AVRQQGDLVR KLKEDKAPQV DVDKAVAELK ARKRVLEAKE LALQPKDDIV DRAKMEDTLK RRFFYDQAFA IYGGVSGLYD FGPVGCALKN NIIQTWRQHF IQEEQILEID CTMLTPEPVL KTSGHVDKFA DFMVKDVKNG ECFRADHLLK AHLQKLMSDK KCSVEKKSEM ESVLAQLDNY GQQELADLFV NYNVKSPITG NDLSPPVSFN LMFKTFIGPG GNMPGYLRPE TAQGIFLNFK RLLEFNQGKL PFAAAQIGNS FRNEISPRSG LIRVREFTMA EIEHFVDPSE KDHPKFQNVA D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-370 of human GARS (NP_002038.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GARS

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Alternative Name: GARS (GARS Products)

Synonyms: CMT2D antibody, DSMAV antibody, GlyRS antibody, HMN5 antibody, SMAD1 antibody, Aat-gly antibody, CG6778 antibody, Dmel\\CG6778 antibody, GRS antibody, gars antibody, team antibody, RGD1559871 antibody, GENA202 antibody, Gena201 antibody, Nmf249 antibody, Sgrp23 antibody, GB13467 antibody, MGC79495 antibody, fb02f03 antibody, si:dkey-276i5.1 antibody, wu:fb02f03 antibody, NI36_08435 antibody, glycyl-tRNA synthetase antibody, Glycyl-tRNA synthetase antibody, glycine--tRNA ligase antibody, glycyl-tRNA synthetase L homeolog antibody, Glycine--tRNA ligase antibody, GARS antibody, GlyRS antibody, Gars antibody, LOC408392 antibody, gars.L antibody, gars antibody, LOC692991 antibody, glyQ antibody, TTHA0543 antibody, NI36_RS08405 antibody

Background: This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.,GARS,CMT2D,DSMAV,GlyRS,HMN5,SMAD1,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,GARS

Molecular Weight: 83 kDa

Gene ID: 2617

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process