GABARAPL1 antibody (AA 1-117)
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- Target See all GABARAPL1 Antibodies
- GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))
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Binding Specificity
- AA 1-117
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GABARAPL1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MKFQYKEDHP FEYRKKEGEK IRKKYPDRVP VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV NNTIPPTSAT MGQLYEDNHE EDYFLYVAYS DESVYGK
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human GABARAPL1 (NP_113600.1).
- Isotype
- IgG
- Top Product
- Discover our top product GABARAPL1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))
- Alternative Name
- GABARAPL1 (GABARAPL1 Products)
- Background
- Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.,GABARAPL1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GEC1,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Regulators,GABARAPL1
- Molecular Weight
- 14 kDa/17 kDa
- Gene ID
- 23710
- UniProt
- Q9H0R8
- Pathways
- Autophagy
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