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GAB2 antibody (AA 377-676)

GAB2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6140869
  • Target See all GAB2 Antibodies
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Binding Specificity
    • 24
    • 21
    • 16
    • 11
    • 10
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 377-676
    Reactivity
    • 123
    • 91
    • 85
    • 3
    • 3
    • 3
    • 3
    Human
    Host
    • 121
    • 2
    • 1
    Rabbit
    Clonality
    • 123
    • 1
    Polyclonal
    Conjugate
    • 40
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This GAB2 antibody is un-conjugated
    Application
    • 85
    • 41
    • 39
    • 39
    • 20
    • 16
    • 13
    • 9
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ENSRSVAATI PRRNTLPAMD NSRLHRASSC ETYEYPQRGG ESAGRSAESM SDGVGSFLPG KMIVGRSDST NSEDNYVPMN PGSSTLLAME RAGDNSQSVY IPMSPGAHHF DSLGYPSTTL PVHRGPSRGS EIQPPPVNRN LKPDRKAKPT PLDLRNNTVI DELPFKSPIT KSWSRANHTF NSSSSQYCRP ISTQSITSTD SGDSEENYVP MQNPVSASPV PSGTNSPAPK KSTGSVDYLA LDFQPSSPSP HRKPSTSSVT SDEKVDYVQV DKEKTQALQN TMQEWTDVRQ SSEPSKGAKL
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 377-676 of human GAB2 (NP_536739.1).
    Isotype
    IgG
    Top Product
    Discover our top product GAB2 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Alternative Name
    GAB2 (GAB2 Products)
    Synonyms
    GAB2 antibody, AI463667 antibody, D130058I17Rik antibody, p97 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GAB2 antibody, gab2 antibody, Gab2 antibody
    Background
    This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.,GAB2,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,GAB2
    Molecular Weight
    69 kDa/74 kDa
    Gene ID
    9846
    UniProt
    Q9UQC2
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
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