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FTO antibody (AA 416-505)

FTO Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6140795
  • Target See all FTO Antibodies
    FTO (Fat Mass and Obesity-Associated (FTO))
    Binding Specificity
    • 18
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 416-505
    Reactivity
    • 64
    • 27
    • 25
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 56
    • 8
    • 1
    • 1
    Rabbit
    Clonality
    • 49
    • 17
    Polyclonal
    Conjugate
    • 31
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FTO antibody is un-conjugated
    Application
    • 53
    • 23
    • 18
    • 14
    • 14
    • 11
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Sequence
    AVLHEVKREG LPVEQRNEIL TAILASLTAR QNLRREWHAR CQSRIARTLP ADQKPECRPY WEKDDASMPL PFDLTDIVSE LRGQLLEAKP
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 416-505 of human FTO (NP_001073901.1).
    Isotype
    IgG
    Top Product
    Discover our top product FTO Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FTO (Fat Mass and Obesity-Associated (FTO))
    Alternative Name
    FTO (FTO Products)
    Synonyms
    AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
    Background
    This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.,FTO,ALKBH9,BMIQ14,GDFD,Epigenetics & Nuclear Signaling,Cancer,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,FTO
    Molecular Weight
    6 kDa/12 kDa/14 kDa/58 kDa
    Gene ID
    79068
    UniProt
    Q9C0B1
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