FTO antibody (AA 416-505)
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- Target See all FTO Antibodies
- FTO (Fat Mass and Obesity-Associated (FTO))
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Binding Specificity
- AA 416-505
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FTO antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Sequence
- AVLHEVKREG LPVEQRNEIL TAILASLTAR QNLRREWHAR CQSRIARTLP ADQKPECRPY WEKDDASMPL PFDLTDIVSE LRGQLLEAKP
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 416-505 of human FTO (NP_001073901.1).
- Isotype
- IgG
- Top Product
- Discover our top product FTO Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IP,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FTO (Fat Mass and Obesity-Associated (FTO))
- Alternative Name
- FTO (FTO Products)
- Synonyms
- AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
- Background
- This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.,FTO,ALKBH9,BMIQ14,GDFD,Epigenetics & Nuclear Signaling,Cancer,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,FTO
- Molecular Weight
- 6 kDa/12 kDa/14 kDa/58 kDa
- Gene ID
- 79068
- UniProt
- Q9C0B1
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