FOXP2 antibody (AA 441-740)

Catalog No. ABIN6140762

Product Details anti-FOXP2 Antibody

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Binding Specificity: AA 441-740

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PKPSPKPLNL VSSVTMSKNM LETSPQSLPQ TPTTPTAPVT PITQGPSVIT PASVPNVGAI RRRHSDKYNI PMSSEIAPNY EFYKNADVRP PFTYATLIRQ AIMESSDRQL TLNEIYSWFT RTFAYFRRNA ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEVEYQKRRS QKITGSPTLV KNIPTSLGYG AALNASLQAA LAESSLPLLS NPGLINNASS GLLQAVHEDL NGSLDHIDSN GNSSPGCSPQ PHIHSIHVKE EPVIAEDEDC PMSLVTTANH SPELEDDREI EEEPLSEDLE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 441-740 of human FOXP2 (NP_683696.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Alternative Name: FOXP2 (FOXP2 Products)

Synonyms: CAGH44 antibody, SPCH1 antibody, TNRC10 antibody, 2810043D05Rik antibody, AI449000 antibody, CAG-16 antibody, D0Kist7 antibody, RGD1559697 antibody, FOXP2 antibody, spch1 antibody, cagh44 antibody, tnrc10 antibody, xlFoxP2 antibody, foxP2 antibody, foxP antibody, Foxp2 antibody, foxP2b antibody, foxp2a antibody, forkhead box P2 antibody, lmw-gs antibody, forkhead box transcription factor antibody, forkhead box P2 L homeolog antibody, FOXP2 antibody, Foxp2 antibody, foxp2 antibody, foxP2 antibody, foxp1c antibody, foxp2.L antibody

Background: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.,FOXP2,CAGH44,SPCH1,TNRC10,Epigenetics & Nuclear Signaling,Transcription Factors,FOXP2

Molecular Weight: 9-18 kDa/40- 48 kDa/70- 82 kDa

Gene ID: 93986

UniProt: O15409