FLT4 antibody (AA 1174-1363)

Catalog No. ABIN6140699

Product Details anti-FLT4 Antibody

Target: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Binding Specificity: AA 1174-1363

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLT4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: QGRGLQEEEE VCMAPRSSQS SEEGSFSQVS TMALHIAQAD AEDSPPSLQR HSLAARYYNW VSFPGCLARG AETRGSSRMK TFEEFPMTPT TYKGSVDNQT DSGMVLASEE FEQIESRHRQ ESGFSCKGPG QNVAVTRAHP DSQGRRRRPE RGARGGQVFY NSEYGELSEP SEEDHCSPSA RVTFFTDNSY

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1174-1363 of human FLT4 (NP_891555.2).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-FLT4 antibody (ABIN6140699)

Yang, Sun, He, Ren, Liu, Liu, Zhang, Zhao: "Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation." in: The American journal of pathology, Vol. 187, Issue 11, pp. 2602-2615, (2017) (PubMed).

Target Details for FLT4

Target: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Alternative Name: FLT4 (FLT4 Products)

Synonyms: FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody

Background: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.,FLT4,FLT-4,FLT41,LMPH1A,PCL,VEGFR-3,VEGFR3,Epigenetics & Nuclear Signaling,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,VEGF,VEGF Receptors,Cardiovascular,Angiogenesis,Angiogenic growth factors,FLT4

Molecular Weight: 93 kDa/145 kDa/152 kDa

Gene ID: 2324

UniProt: P35916

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling