FLNC antibody (AA 2160-2340)

Catalog No. ABIN6140681

Product Details anti-FLNC Antibody

Target: FLNC (Filamin C, gamma (FLNC))

Binding Specificity: AA 2160-2340

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLNC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: IPGNWFQMVS AQERLTRTFT RSSHTYTRTE RTEISKTRGG ETKREVRVEE STQVGGDPFP AVFGDFLGRE RLGSFGSITR QQEGEASSQD MTAQVTSPSG KVEAAEIVEG EDSAYSVRFV PQEMGPHTVA VKYRGQHVPG SPFQFTVGPL GEGGAHKVRA GGTGLERGVA GVPAEFSIWT R

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2160-2340 of human FLNC (NP_001449.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FLNC

Target: FLNC (Filamin C, gamma (FLNC))

Alternative Name: FLNC (FLNC Products)

Synonyms: 1110055E19Rik antibody, ABP-280 antibody, ABPL antibody, Fln2 antibody, ABP280A antibody, ABPA antibody, FLN2 antibody, MFM5 antibody, MPD4 antibody, filamin C antibody, filamin C L homeolog antibody, filamin C, gamma antibody, FLNC antibody, flnc.L antibody, flnc antibody, Flnc antibody

Background: This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.,FLNC,ABP-280,ABP280A,ABPA,ABPL,CMH26,FLN2,MFM5,MPD4,RCM5,filamin-C,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,FLNC

Molecular Weight: 287 kDa/291 kDa

Gene ID: 2318

UniProt: Q14315