FDPS antibody (AA 120-419)

Catalog No. ABIN6140569

Product Details anti-FDPS Antibody

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Binding Specificity: AA 120-419

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDPS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IGGKYNRGLT VVVAFRELVE PRKQDADSLQ RAWTVGWCVE LLQAFFLVAD DIMDSSLTRR GQICWYQKPG VGLDAINDAN LLEACIYRLL KLYCREQPYY LNLIELFLQS SYQTEIGQTL DLLTAPQGNV DLVRFTEKRY KSIVKYKTAF YSFYLPIAAA MYMAGIDGEK EHANAKKILL EMGEFFQIQD DYLDLFGDPS VTGKIGTDIQ DNKCSWLVVQ CLQRATPEQY QILKENYGQK EAEKVARVKA LYEELDLPAV FLQYEEDSYS HIMALIEQYA APLPPAVFLG LARKIYKRRK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-419 of human FDPS (NP_001129293.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Alternative Name: FDPS (FDPS Products)

Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.,FDPS,FPPS,FPS,POROK9,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,FDPS

Molecular Weight: 40 kDa/48 kDa

Gene ID: 2224

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation