FcRn antibody (AA 25-300)

Catalog No. ABIN6140552

Product Details anti-FcRn Antibody

Target: FcRn (IgG receptor FcRn (FcRn))

Binding Specificity: AA 25-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FcRn antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: ESHLSLLYHL TAVSSPAPGT PAFWVSGWLG PQQYLSYNSL RGEAEPCGAW VWENQVSWYW EKETTDLRIK EKLFLEAFKA LGGKGPYTLQ GLLGCELGPD NTSVPTAKFA LNGEEFMNFD LKQGTWGGDW PEALAISQRW QQQDKAANKE LTFLLFSCPH RLREHLERGR GNLEWKEPPS MRLKARPSSP GFSVLTCSAF SFYPPELQLR FLRNGLAAGT GQGDFGPNSD GSFHASSSLT VKSGDEHHYC CIVQHAGLAQ PLRVELESPA KSSVLV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-300 of human FCGRT (NP_004098.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FcRn

Target: FcRn (IgG receptor FcRn (FcRn))

Alternative Name: FCGRT (FcRn Products)

Synonyms: FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody

Background: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.,FCGRT,FCRN,alpha-chain,Immunology & Inflammation,FCGRT

Molecular Weight: 39 kDa

Gene ID: 2217

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process