FANCM antibody (AA 390-660)

Catalog No. ABIN6140478

The Rabbit Polyclonal anti-FANCM antibody has been validated for WB and IF. It is suitable to detect FANCM in samples from Human.

Quick Overview for FANCM antibody (AA 390-660) (ABIN6140478)

Target: FANCM (Fanconi Anemia Complementation Group M (FANCM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-FANCM Antibody

Binding Specificity: AA 390-660

Sequence: MDGTKGMTRS KNELGRNEDF MKLYNHLECM FARTRSTSAN GISAIQQGDK NKKFVYSHPK LKKLEEVVIE HFKSWNAENT TEKKRDETRV MIFSSFRDSV QEIAEMLSQH QPIIRVMTFV GHASGKSTKG FTQKEQLEVV KQFRDGGYNT LVSTCVGEEG LDIGEVDLII CFDSQKSPIR LVQRMGRTGR KRQGRIVIIL SEGREERIYN QSQSNKRSIY KAISSNRQVL HFYQRSPRMV PDGINPKLHK MFITHGVYEP EKPSRNLQRK S

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 390-660 of human FANCM (NP_065988.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FANCM

Target: FANCM (Fanconi Anemia Complementation Group M (FANCM))

Alternative Name: FANCM

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants.,FANCM,FAAP250,KIAA1596,Epigenetics & Nuclear Signaling,DNA Damage & Repair,FANCM

Molecular Weight: 75 kDa/229 kDa/232 kDa

Gene ID: 57697

UniProt: Q8IYD8

Pathways: DNA Damage Repair