FA2H antibody (AA 95-170)

Catalog No. ABIN6140410

Product Details anti-FA2H Antibody

Target: FA2H (Fatty Acid 2-Hydroxylase (FA2H))

Binding Specificity: AA 95-170

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FA2H antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NEPVALEETQ KTDPAMEPRF KVVDWDKDLV DWRKPLLWQV GHLGEKYDEW VHQPVTRPIR LFHSDLIEGL SKTVWY

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 95-170 of human FA2H (NP_077282.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FA2H

Target: FA2H (Fatty Acid 2-Hydroxylase (FA2H))

Alternative Name: FA2H (FA2H Products)

Background: This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.,FA2H,FAAH,FAH1,FAXDC1,SCS7,SPG35,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Cell Type Marker,Neuron marker,Axon marker,FA2H

Molecular Weight: 18 kDa/42 kDa

Gene ID: 79152

UniProt: Q7L5A8