ERCC3 antibody (AA 512-782)
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- Target See all ERCC3 Antibodies
- ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
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Binding Specificity
- AA 512-782
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERCC3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CPMSPEFYRE YVAIKTKKRI LLYTMNPNKF RACQFLIKFH ERRNDKIIVF ADNVFALKEY AIRLNKPYIY GPTSQGERMQ ILQNFKHNPK INTIFISKVG DTSFDLPEAN VLIQISSHGG SRRQEAQRLG RVLRAKKGMV AEEYNAFFYS LVSQDTQEMA YSTKRQRFLV DQGYSFKVIT KLAGMEEEDL AFSTKEEQQQ LLQKVLAATD LDAEEEVVAG EFGSRSSQAS RRFGTMSSMS GADDTVYMEY HSSRSKAPSK HVHPLFKRFR K
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 512-782 of human ERCC3 (NP_000113.1).
- Isotype
- IgG
- Top Product
- Discover our top product ERCC3 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
- Alternative Name
- ERCC3 (ERCC3 Products)
- Background
- This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.,ERCC3,BTF2,GTF2H,RAD25,TFIIH,TTD2,XPB,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,ERCC3
- Molecular Weight
- 89 kDa
- Gene ID
- 2071
- UniProt
- P19447
- Pathways
- DNA Damage Repair
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