EPH Receptor A2 antibody (AA 847-976)

Catalog No. ABIN6140210

Product Details anti-EPH Receptor A2 Antibody

Target: EPH Receptor A2 (EPHA2)

Binding Specificity: AA 847-976

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YQLMMQCWQQ ERARRPKFAD IVSILDKLIR APDSLKTLAD FDPRVSIRLP STSGSEGVPF RTVSEWLESI KMQQYTEHFM AAGYTAIEKV VQMTNDDIKR IGVRLPGHQK RIAYSLLGLK DQVNTVGIPI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 847-976 of human EPHA2 (NP_004422.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2 (EPHA2 Products)

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.,ARCC2,CTPA,CTPP1,CTRCT6,ECK,EPHA2,Signal Transduction,Kinase,Tyrosine kinases,Neuroscience,Cell Type Marker,Cardiovascular,Angiogenesis,Neuron marker,Growth Cone,EPHA2

Molecular Weight: 54 kDa/108 kDa

Gene ID: 1969

UniProt: P29317

Pathways: RTK Signaling