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EP400 antibody (AA 90-330)

EP400 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6140195
  • Target See all EP400 Antibodies
    EP400 (E1A Binding Protein P400 (EP400))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 90-330
    Reactivity
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 5
    • 4
    Rabbit
    Clonality
    • 7
    • 2
    Polyclonal
    Conjugate
    • 9
    This EP400 antibody is un-conjugated
    Application
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TLAPLPLPSP TSPGFQFSAQ PRRFEHGSPS YIQVTSPLSQ QVQTQSPTQP SPGPGQALQN VRAGAPGPGL GLCSSSPTGG FVDASVLVRQ ISLSPSSGGH FVFQDGSGLT QIAQGAQVQL QHPGTPITVR ERRPSQPHTQ SGGTIHHLGP QSPAAAGGAG LQPLASPSHI TTANLPPQIS SIIQGQLVQQ QQVLQGPPLP RPLGFERTPG VLLPGAGGAA GFGMTSPPPP TSPSRTAVPP G
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 90-330 of human EP400 (NP_056224.3).
    Isotype
    IgG
    Top Product
    Discover our top product EP400 Primary Antibody
  • Application Notes
    WB,1:500 - 1:1000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    EP400 (E1A Binding Protein P400 (EP400))
    Alternative Name
    EP400 (EP400 Products)
    Synonyms
    CAGH32 antibody, P400 antibody, TNRC12 antibody, 1700020J09Rik antibody, AU023439 antibody, mDomino antibody, mKIAA1498 antibody, p400 antibody, E1A binding protein p400 antibody, EP400 N-terminal-like protein antibody, helicase domino antibody, E1a binding protein P400 antibody, EP400 antibody, Ep400 antibody, LOC738562 antibody, LOC5570719 antibody, CpipJ_CPIJ007689 antibody, CpipJ_CPIJ007688 antibody, CpipJ_CPIJ007686 antibody, CpipJ_CPIJ008061 antibody
    Background
    Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.,EP400,CAGH32,P400,TNRC12,Epigenetics & Nuclear Signaling,Chromatin Remodeling,EP400
    Molecular Weight
    331 kDa/335 kDa/339 kDa/343 kDa
    Gene ID
    57634
    UniProt
    Q96L91
    Pathways
    Chromatin Binding
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