EIF3H antibody (AA 80-340)

Catalog No. ABIN6140064

Product Details anti-EIF3H Antibody

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Binding Specificity: AA 80-340

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: NCFPFPQHTE DDADFDEVQY QMEMMRSLRH VNIDHLHVGW YQSTYYGSFV TRALLDSQFS YQHAIEESVV LIYDPIKTAQ GSLSLKAYRL TPKLMEVCKE KDFSPEALKK ANITFEYMFE EVPIVIKNSH LINVLMWELE KKSAVADKHE LLSLASSNHL GKNLQLLMDR VDEMSQDIVK YNTYMRNTSK QQQQKHQYQQ RRQQENMQRQ SRGEPPLPEE DLSKLFKPPQ PPARMDSLLI AGQINTYCQN IKEFTAQNLG K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human EIF3H (NP_003747.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EIF3H

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Alternative Name: EIF3H (EIF3H Products)

Synonyms: EIF3S3 antibody, eIF3-gamma antibody, eIF3-p40 antibody, 1110008A16Rik antibody, 40kD antibody, 9430017H16Rik antibody, EIF3-P40 antibody, EIF3-gamma antibody, Eif3s3 antibody, eif3s3 antibody, eIF-3p40 antibody, En10 antibody, AO090038000435 antibody, EIF3H antibody, eIF3h antibody, BcDNA:GM14618 antibody, CG9124 antibody, Dmel\\CG9124 antibody, eIF-3 antibody, eIF3-S3 antibody, eIf3-p44 antibody, l(2)k09003 antibody, eIF3h-A antibody, eif3h antibody, fj02c04 antibody, wu:fj02c04 antibody, zgc:101085 antibody, eIF3h-B antibody, zgc:123049 antibody, eukaryotic translation initiation factor 3 subunit H antibody, eukaryotic translation initiation factor 3, subunit H antibody, eukaryotic translation initiation factor 3 subunit H S homeolog antibody, eukaryotic translation initiation factor 3 subunit H-like antibody, Eukaryotic initiation factor 3 p40 subunit antibody, eukaryotic translation initiation factor 3, subunit H, a antibody, Eukaryotic translation initiation factor 3 subunit H antibody, translation initiation factor eIF3h (p40) antibody, eukaryotic translation initiation factor 3, subunit H, b antibody, EIF3H antibody, Eif3h antibody, eif3h antibody, eif3h.S antibody, eIF3h antibody, AOR_1_722074 antibody, PAAG_02837 antibody, VDBG_01433 antibody, MGYG_06658 antibody, LOC100196680 antibody, eIF-3p40 antibody, eif3ha antibody, eif-3.H antibody, SPAC821.05 antibody, eif3hb antibody

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3H,EIF3S3,eIF3-gamma,eIF3-p40,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,EIF3H

Molecular Weight: 39 kDa

Gene ID: 8667

UniProt: O15372

Pathways: Ribonucleoprotein Complex Subunit Organization