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Endothelin 3 antibody (AA 17-187)

EDN3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6139934
  • Target See all Endothelin 3 (EDN3) Antibodies
    Endothelin 3 (EDN3)
    Binding Specificity
    • 10
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 17-187
    Reactivity
    • 35
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 34
    • 3
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Endothelin 3 antibody is un-conjugated
    Application
    • 26
    • 18
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    AGFVPCSQSG DAGRRGVSQA PTAARSEGDC EETVAGPGEE TVAGPGEGTV APTALQGPSP GSPGQEQAAE GAPEHHRSRR CTCFTYKDKE CVYYCHLDII WINTPEQTVP YGLSNYRGSF RGKRSAGPLP GNLQLSHRPH LRCACVGRYD KACLHFCTQT LDVSSNSRTA E
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 17-187 of human EDN3 (NP_996917.1).
    Isotype
    IgG
    Top Product
    Discover our top product EDN3 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Endothelin 3 (EDN3)
    Alternative Name
    EDN3 (EDN3 Products)
    Synonyms
    et-3 antibody, EDN3 antibody, ET-3 antibody, ET3 antibody, HSCR4 antibody, PPET3 antibody, WS4B antibody, 114CH19 antibody, ls antibody, tmgc48 antibody, Et3 antibody, RGD1564825 antibody, preproET-3 antibody, endothelin-3 L homeolog antibody, endothelin 3 antibody, edn3.L antibody, EDN3 antibody, Edn3 antibody
    Background
    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.,EDN3,ET-3,ET3,HSCR4,PPET3,WS4B,Cancer,Invasion and Metastasis,Signal Transduction,Neuroscience,EDN3
    Molecular Weight
    23 kDa/25 kDa
    Gene ID
    1908
    UniProt
    P14138
    Pathways
    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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