DMRT1 antibody (AA 134-373)

Catalog No. ABIN6139687

Product Details anti-DMRT1 Antibody

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Binding Specificity: AA 134-373

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMRT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SHPIPLPSAA ELLVKRENNG SNPCLMTECS GTSQPPPASV PTTAASEGRM VIQDIPAVTS RGHVENTPDL VSDSTYYSSF YQPSLFPYYN NLYNCPQYSM ALAADSASGE VGNPLGGSPV KNSLRGLPGP YVPGQTGNQW QMKNMENRHA MSSQYRMHSY YPPPSYLGQS VPQFFTFEDA PSYPEARASV FSPPSSQDSG LVSLSSSSPI SNKSTKAVLE CEPASEPSSF TVTPVIEEDE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 134-373 of human DMRT1 (NP_068770.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DMRT1

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Alternative Name: DMRT1 (DMRT1 Products)

Background: This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.,DMRT1,CT154,DMT1,Epigenetics & Nuclear Signaling,Transcription Factors,DMRT1

Molecular Weight: 18 kDa/28 kDa/39 kDa

Gene ID: 1761

UniProt: Q9Y5R6