DIRAS3 antibody (AA 1-229)

Catalog No. ABIN6139629

Product Details anti-DIRAS3 Antibody

Target: DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))

Binding Specificity: AA 1-229

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIRAS3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGNASFGSKE QKLLKRLRLL PALLILRAFK PHRKIRDYRV VVVGTAGVGK STLLHKWASG NFRHEYLPTI ENTYCQLLGC SHGVLSLHIT DSKSGDGNRA LQRHVIARGH AFVLVYSVTK KETLEELKAF YELICKIKGN NLHKFPIVLV GNKSDDTHRE VALNDGATCA MEWNCAFMEI SAKTDVNVQE LFHMLLNYKK KPTTGLQEPE KKSQMPNTTE KLLDKCIIM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human DIRAS3 (NP_004666.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DIRAS3

Target: DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))

Alternative Name: DIRAS3 (DIRAS3 Products)

Synonyms: DIRAS3 antibody, arhi antibody, noey2 antibody, ARHI antibody, NOEY2 antibody, DIRAS family GTPase 3 antibody, DIRAS family GTP binding RAS like 3 antibody, DIRAS3 antibody, diras3 antibody

Background: This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.,DIRAS3,ARHI,NOEY2,Cancer,Tumor suppressors,DIRAS3

Molecular Weight: 25 kDa

Gene ID: 9077

UniProt: O95661