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DERL1 antibody (AA 182-251)

DERL1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6139538
  • Target See all DERL1 Antibodies
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    Binding Specificity
    • 15
    • 9
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 182-251
    Reactivity
    • 37
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 1
    Rabbit
    Clonality
    • 36
    • 1
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DERL1 antibody is un-conjugated
    Application
    • 21
    • 16
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LYFFLMFRYP MDLGGRNFLS TPQFLYRWLP SRRGGVSGFG VPPASMRRAA DQNGGGGRHN WGQGFRLGDQ
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 182-251 of human DERL1 (NP_077271.1).
    Isotype
    IgG
    Top Product
    Discover our top product DERL1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    Alternative Name
    DERL1 (DERL1 Products)
    Synonyms
    CG10908 antibody, Dmel\\CG10908 antibody, DDBDRAFT_0188135 antibody, DDBDRAFT_0266772 antibody, DDB_0188135 antibody, DDB_0266772 antibody, MGC84200 antibody, wu:fb09d07 antibody, wu:fb94d05 antibody, wu:fj92g12 antibody, zgc:55637 antibody, 1110021N07Rik antibody, AI195141 antibody, AW551338 antibody, Derlin-1 antibody, derlin-1 antibody, DER-1 antibody, DER1 antibody, RGD1311835 antibody, DERLIN-1 antibody, F17A13.150 antibody, F17A13_150 antibody, Derlin-1 antibody, derlin-1 antibody, derlin-1.1 antibody, hypothetical protein antibody, Der1-like domain family, member 1 antibody, derlin 1 antibody, derlin 1 L homeolog antibody, DERLIN-1 antibody, Der-1 antibody, EDI_023440 antibody, PTRG_01331 antibody, derl1 antibody, DERL1 antibody, derl1.L antibody, Derl1 antibody, DER1 antibody
    Background
    The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms.,DERL1,DER-1,DER1,derlin-1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,DERL1
    Molecular Weight
    26 kDa/28 kDa
    Gene ID
    79139
    UniProt
    Q9BUN8
    Pathways
    ER-Nucleus Signaling
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