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DDX58 antibody (AA 726-925)
DDX58
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DDX58 Antibody
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Target
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DDX58
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
Binding Specificity
All epitopes for DDX58 antibodies
AA 726-925
Reactivity
All reactivities for DDX58 antibodies
Human
Host
All hosts for DDX58 antibodies
Rabbit
Clonality
All clonalities for DDX58 antibodies
Polyclonal
Conjugate
All conjugates for DDX58 antibodies
This DDX58 antibody is un-conjugated
Application
All applications for DDX58 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Sequence
QTRGRGRARG SKCFLLTSNA GVIEKEQINM YKEKMMNDSI LRLQTWDEAV FREKILHIQT HEKFIRDSQE KPKPVPDKEN KKLLCRKCKA LACYTADVRV IEECHYTVLG DAFKECFVSR PHPKPKQFSS FEKRAKIFCA RQNCSHDWGI HVKYKTFEIP VIKIESFVVE DIATGVQTLY SKWKDFHFEK IPFDPAEMSK
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 726-925 of human RIG-I / DDX58 (NP_055129.2).
Isotype
IgG
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Discover our top product DDX58 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for DDX58
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Target
DDX58
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
Alternative Name
DDX58 (DDX58 Products )
Synonyms
RIG-I antibody, RIGI antibody, RLR-1 antibody, 6430573D20Rik antibody, C330021E21 antibody, RHIV-1 antibody, RIG-1 antibody, DExD/H-box helicase 58 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 antibody, DEXD/H-box helicase 58 antibody, DDX58 antibody, Ddx58 antibody
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.,DDX58,RIG-I,RIGI,RLR-1,SGMRT2,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,DDX58
Molecular Weight
101 kDa/106 kDa
Gene ID
23586
UniProt
O95786
Pathways
Activation of Innate immune Response , Hepatitis C
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