DDOST antibody (AA 40-300)

Catalog No. ABIN6139469

Product Details anti-DDOST Antibody

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Binding Specificity: AA 40-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDOST antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VCASGPRTLV LLDNLNVRET HSLFFRSLKD RGFELTFKTA DDPSLSLIKY GEFLYDNLII FSPSVEDFGG NINVETISAF IDGGGSVLVA ASSDIGDPLR ELGSECGIEF DEEKTAVIDH HNYDISDLGQ HTLIVADTEN LLKAPTIVGK SSLNPILFRG VGMVADPDNP LVLDILTGSS TSYSFFPDKP ITQYPHAVGK NTLLIAGLQA RNNARVIFSG SLDFFSDSFF NSAVQKAAPG SQRYSQTGNY ELAVALSRWV F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human DDOST (NP_005207.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DDOST

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Alternative Name: DDOST (DDOST Products)

Background: This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.,DDOST,AGER1,CDG1R,GATD6,OKSWcl45,OST,OST48,WBP1,DDOST

Molecular Weight: 46 kDa/49 kDa/50 kDa

Gene ID: 1650

UniProt: P39656

Pathways: Cell RedoxHomeostasis