The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.,DBN1,D0S117E,drebrin,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Microfilaments,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neuron marker,Dendrite marker,Growth Cone,DBN1