DAZL antibody (AA 186-295)

Catalog No. ABIN6139416

Product Details anti-DAZL Antibody

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Binding Specificity: AA 186-295

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: VYNYQMPPQW PVGEQRSYVV PPAYSAVNYH CNEVDPGAEV VPNECSVHEA TPPSGNGPQK KSVDRSIQTV VSCLFNPENR LRNSVVTQDD YFKDKRVHHF RRSRAMLKSV

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL (NP_001342.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DAZL

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Alternative Name: DAZL (DAZL Products)

Synonyms: DAZH antibody, DAZL1 antibody, DAZLA antibody, SPGYLA antibody, DAZL antibody, Xdazl antibody, dazh antibody, dazl1 antibody, dazla antibody, spgyla antibody, dazl-B antibody, dazl-a antibody, Daz-like antibody, Dazh antibody, Dazl1 antibody, Dazla antibody, Tpx-2 antibody, Tpx2 antibody, deleted in azoospermia like antibody, deleted in azoospermia-like antibody, deleted in azoospermia-like L homeolog antibody, DAZL antibody, dazl antibody, Dazl antibody, dazl.L antibody

Background: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.,DAZL,DAZH,DAZL1,DAZLA,SPGYLA,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,DAZL

Molecular Weight: 33 kDa/35 kDa

Gene ID: 1618

UniProt: Q92904