DARS antibody (AA 222-501)

Catalog No. ABIN6139407

Product Details anti-DARS Antibody

Target: DARS (Aspartyl-tRNA Synthetase (DARS))

Binding Specificity: AA 222-501

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: KIISAASEGG ANVFTVSYFK NNAYLAQSPQ LYKQMCICAD FEKVFSIGPV FRAEDSNTHR HLTEFVGLDI EMAFNYHYHE VMEEIADTMV QIFKGLQERF QTEIQTVNKQ FPCEPFKFLE PTLRLEYCEA LAMLREAGVE MGDEDDLSTP NEKLLGHLVK EKYDTDFYIL DKYPLAVRPF YTMPDPRNPK QSNSYDMFMR GEEILSGAQR IHDPQLLTER ALHHGIDLEK IKAYIDSFRF GAPPHAGGGI GLERVTMLFL GLHNVRQTSM FPRDPKRLTP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 222-501 of human DARS (NP_001340.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DARS

Target: DARS (Aspartyl-tRNA Synthetase (DARS))

Alternative Name: DARS (DARS Products)

Background: This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants.,DARS,HBSL,aspRS,Epigenetics & Nuclear Signaling,RNA Binding,Endocrine & Metabolism,Mitochondrial metabolism,DARS

Molecular Weight: 45 kDa/57 kDa

Gene ID: 1615

UniProt: P14868