Dystroglycan antibody (AA 654-749)

Catalog No. ABIN6139391

Product Details anti-Dystroglycan Antibody

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Binding Specificity: AA 654-749

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystroglycan antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: SIVVEWTNNT LPLEPCPKEQ IAGLSRRIAE DDGKPRPAFS NALEPDFKAT SITVTGSGSC RHLQFIPVVP PRRVPSEAPP TEVPDRDPEK SSEDDV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 654-749 of human DAG1 (NP_004384.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IF,1:20 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dystroglycan

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Alternative Name: DAG1 (DAG1 Products)

Background: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.,156DAG,A3a,AGRNR,DAG,MDDGA9,MDDGC7,MDDGC9,DAG1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Neuroscience,DAG1

Molecular Weight: 97 kDa

Gene ID: 1605

UniProt: Q14118

Pathways: Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus