CWC22 antibody (AA 639-908)

Catalog No. ABIN6139263

This anti-CWC22 antibody is a Rabbit Polyclonal antibody detecting CWC22 in WB. Suitable for Human.

Quick Overview for CWC22 antibody (AA 639-908) (ABIN6139263)

Target: CWC22 (CWC22 Spliceosome-Associated Protein Homolog (CWC22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CWC22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CWC22 Antibody

Binding Specificity: AA 639-908

Sequence: LTDELREHLK NTPKVIVAQK PDVEQNKSSP SSSSSASSSS ESDSSDSDSD SSDSSSESSS EESDSSSISS HSSASANDVR KKGHGKTRSK EVDKLIRNQQ TNDRKQKERR QEHGHQETRT ERERRSEKHR DQNSSGSNWR DPITKYTSDK DVPSERNNYS RVANDRDQEM HIDLENKHGD PKKKRGERRN SFSENEKHTH RIKDSENFRR KDRSKSKEMN RKHSGSRSDE DRYQNGAERR WEKSSRYSEQ SRESKKNQDR RREKSPAKQK

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 639-908 of human CWC22 (NP_065994.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CWC22

Target: CWC22 (CWC22 Spliceosome-Associated Protein Homolog (CWC22))

Alternative Name: CWC22

Background: Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.,CWC22,EIF4GL,NCM,fSAPb,Epigenetics & Nuclear Signaling,CWC22

Molecular Weight: 105 kDa

Gene ID: 57703

UniProt: Q9HCG8