Cullin 4B antibody (AA 1-200)

Catalog No. ABIN6139255

Product Details anti-Cullin 4B Antibody

Target: Cullin 4B (CUL4B)

Binding Specificity: AA 1-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MMSQSSGSGD GNDDEATTSK DGGFSSPSPS AAAAAQEVRS ATDGNTSTTP PTSAKKRKLN SSSSSSSNSS NEREDFDSTS SSSSTPPLQP RDSASPSTSS FCLGVSVAAS SHVPIQKKLR FEDTLEFVGF DAKMAEESSS SSSSSSPTAA TSQQQQLKNK SILISSVASV HHANGLAKSS TTVSSFANSK PGSAKKLVIK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CUL4B (NP_003579.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cullin 4B

Target: Cullin 4B (CUL4B)

Alternative Name: CUL4B (CUL4B Products)

Synonyms: MRXHF2 antibody, MRXS15 antibody, MRXSC antibody, SFM2 antibody, 2700050M05Rik antibody, AA409770 antibody, CUL-4B antibody, mKIAA0695 antibody, RGD1564494 antibody, im:7140950 antibody, im:7150765 antibody, MGC115611 antibody, Tb03.1J15.620 antibody, sfm2 antibody, mrxsc antibody, mrxhf2 antibody, cullin 4B antibody, cullin 4B S homeolog antibody, CUL4B antibody, Cul4b antibody, cul4b antibody, cul4b.S antibody, Tb927.3.1290 antibody

Background: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.,CUL4B,CUL-4B,MRXHF2,MRXS15,MRXSC,SFM2,cullin-4B,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CUL4B

Molecular Weight: 84 kDa/102 kDa/103 kDa

Gene ID: 8450

UniProt: Q13620