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Cathepsin K antibody (AA 115-329)
CTSK
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Cathepsin K Antibody
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Target
See all Cathepsin K (CTSK) Antibodies
Cathepsin K (CTSK)
Binding Specificity
All epitopes for Cathepsin K antibodies
AA 115-329
Reactivity
All reactivities for Cathepsin K antibodies
Human
Host
All hosts for Cathepsin K antibodies
Rabbit
Clonality
All clonalities for Cathepsin K antibodies
Polyclonal
Conjugate
All conjugates for Cathepsin K antibodies
This Cathepsin K antibody is un-conjugated
Application
All applications for Cathepsin K antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
APDSVDYRKK GYVTPVKNQG QCGSCWAFSS VGALEGQLKK KTGKLLNLSP QNLVDCVSEN DGCGGGYMTN AFQYVQKNRG IDSEDAYPYV GQEESCMYNP TGKAAKCRGY REIPEGNEKA LKRAVARVGP VSVAIDASLT SFQFYSKGVY YDESCNSDNL NHAVLAVGYG IQKGNKHWII KNSWGENWGN KGYILMARNK NNACGIANLA SFPKM
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 115-329 of human CTSK (NP_000387.1).
Isotype
IgG
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Discover our top product CTSK Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:100 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Cathepsin K
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Target
Cathepsin K (CTSK)
Alternative Name
CTSK (CTSK Products )
Synonyms
CTS02 antibody, CTSO antibody, CTSO1 antibody, CTSO2 antibody, PKND antibody, PYCD antibody, AI323530 antibody, MMS10-Q antibody, Ms10q antibody, catK antibody, CTSK antibody, wu:fa95f03 antibody, wu:fb08b05 antibody, zgc:110367 antibody, cts02 antibody, ctso antibody, ctso1 antibody, ctso2 antibody, pknd antibody, pycd antibody, OC-2 antibody, catk antibody, cathepsin K antibody, cathepsin K L homeolog antibody, Cathepsin K antibody, CTSK antibody, Ctsk antibody, ctsk antibody, ctsk.L antibody, catk antibody
Background
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.,CTSK,CTS02,CTSO,CTSO1,CTSO2,PKND,PYCD,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Ubiquitin,Neuroscience,Cardiovascular,Angiogenesis,CTSK
Molecular Weight
36 kDa
Gene ID
1513
UniProt
P43235
Pathways
Activation of Innate immune Response , Toll-Like Receptors Cascades
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