CK1 epsilon antibody (AA 247-416)

Catalog No. ABIN6139116

Product Details anti-CK1 epsilon Antibody

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Binding Specificity: AA 247-416

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CK1 epsilon antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: EFSTYLNFCR SLRFDDKPDY SYLRQLFRNL FHRQGFSYDY VFDWNMLKFG AARNPEDVDR ERREHEREER MGQLRGSATR ALPPGPPTGA TANRLRSAAE PVASTPASRI QPAGNTSPRA ISRVDRERKV SMRLHRGAPA NVSSSDLTGR QEVSRIPASQ TSVPFDHLGK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 247-416 of human CSNK1E (NP_689407.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CK1 epsilon antibody (ABIN6139116)

Liu, Chen, Wu, Gao, Zhuang, Chen, Cai, Zhang, Guo, Lin, Zhao, Lin: "CALCB splice region pathogenic variants leading to plasma cell neurotropic enrichment in type 1 autoimmune pancreatitis." in: Cell death & disease, Vol. 8, Issue 2, pp. e2591, (2017) (PubMed).

Target Details for CK1 epsilon

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Alternative Name: CSNK1E (CSNK1E Products)

Background: The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.,CSNK1E,CKIepsilon,HCKIE,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Hedgehog Signaling Pathway,Hippo Signaling Pathway,Wnt/β-Catenin Signaling Pathway,CSNK1E

Molecular Weight: 47 kDa

Gene ID: 1454

UniProt: P49674

Pathways: Hedgehog Signaling, M Phase