COPS3 antibody (AA 194-423)

Catalog No. ABIN6138879

Product Details anti-COPS3 Antibody

Target: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Binding Specificity: AA 194-423

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: GLKNFERALY FYEQAITTPA MAVSHIMLES YKKYILVSLI LLGKVQQLPK YTSQIVGRFI KPLSNAYHEL AQVYSTNNPS ELRNLVNKHS ETFTRDNNMG LVKQCLSSLY KKNIQRLTKT FLTLSLQDMA SRVQLSGPQE AEKYVLHMIE DGEIFASINQ KDGMVSFHDN PEKYNNPAML HNIDQEMLKC IELDERLKAM DQEITVNPQF VQKSMGSQED DSGNKPSSYS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 194-423 of human COPS3 (NP_003644.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COPS3

Target: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Alternative Name: COPS3 (COPS3 Products)

Background: The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene.,COPS3,CSN3,SGN3,Kinase,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,COPS3

Molecular Weight: 45 kDa/47 kDa

Gene ID: 8533

UniProt: Q9UNS2

Pathways: Cell Division Cycle