COL11A2 antibody (AA 210-380)

Catalog No. ABIN6138835

Product Details anti-COL11A2 Antibody

Target: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Binding Specificity: AA 210-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL11A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IVPGVQAAYE SCEQKELECE GGQRERPQNQ QPHRAQRSPQ QQPSRLHRPQ NQEPQSQPTE SLYYDYEPPY YDVMTTGTTP DYQDPTPGEE EEILESSLLP PLEEEQTDLQ VPPTADRFQA EEYGEGGTDP PEGPYDYTYG YGDDYREETE LGPALSAETA HSGAAAHGPR G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_542411.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COL11A2

Target: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Alternative Name: COL11A2 (COL11A2 Products)

Synonyms: col11a2 antibody, MGC89039 antibody, COL11A2 antibody, RING3 antibody, DFNA13 antibody, DFNB53 antibody, FBCG2 antibody, HKE5 antibody, PARP antibody, STL3 antibody, collagen, type XI, alpha 2 antibody, collagen type XI alpha 2 chain antibody, bromodomain containing 2 antibody, col11a2 antibody, COL11A2 antibody, BRD2 antibody, Col11a2 antibody

Background: This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.,COL11A2,DFNA13,DFNB53,FBCG2,HKE5,PARP,STL3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Collagen,Bone,Neuroscience,COL11A2

Molecular Weight: 31 kDa/159-171 kDa

Gene ID: 1302

UniProt: P13942

Pathways: RTK Signaling, Sensory Perception of Sound, Chromatin Binding