CLPS antibody (AA 18-112)

Catalog No. ABIN6138743

Product Details anti-CLPS Antibody

Target: CLPS (Colipase, Pancreatic (CLPS))

Binding Specificity: AA 18-112

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLPS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: APGPRGIIIN LENGELCMNS AQCKSNCCQH SSALGLARCT SMASENSECS VKTLYGIYYK CPCERGLTCE GDKTIVGSIT NTNFGICHDA GRSKQ

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-112 of human CLPS (NP_001823.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLPS

Target: CLPS (Colipase, Pancreatic (CLPS))

Alternative Name: CLPS (CLPS Products)

Synonyms: CLPS antibody, 2200003J09Rik antibody, COLQ antibody, colipase antibody, colipase, pancreatic antibody, CLPS antibody, Clps antibody

Background: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.,CLPS,colipase,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Lipases,Cardiovascular,Lipids,CLPS

Molecular Weight: 11 kDa

Gene ID: 1208

UniProt: P04118

Pathways: Lipid Metabolism