CLK2 antibody (AA 239-498)

Catalog No. ABIN6138733

Product Details anti-CLK2 Antibody

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Binding Specificity: AA 239-498

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLK2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CISFELLGLS TFDFLKDNNY LPYPIHQVRH MAFQLCQAVK FLHDNKLTHT DLKPENILFV NSDYELTYNL EKKRDERSVK STAVRVVDFG SATFDHEHHS TIVSTRHYRA PEVILELGWS QPCDVWSIGC IIFEYYVGFT LFQTHDNREH LAMMERILGP IPSRMIRKTR KQKYFYRGRL DWDENTSAGR YVRENCKPLR RYLTSEAEEH HQLFDLIESM LEYEPAKRLT LGEALQHPFF ARLRAEPPNK LWDSSRDISR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 239-498 of human CLK2 (NP_003984.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Alternative Name: CLK2 (CLK2 Products)

Synonyms: MGC53993 antibody, hclk2 antibody, clk2 antibody, fb20c02 antibody, si:ch211-81a5.7 antibody, wu:fb20c02 antibody, MGC131228 antibody, hCLK2 antibody, AU041688 antibody, Tu52 antibody, CDC like kinase 2 antibody, CDC like kinase 2 S homeolog antibody, CDC-like kinase 2a antibody, CDC like kinase 2 L homeolog antibody, CDC-like kinase 2 antibody, CLK2 antibody, clk2.S antibody, clk2 antibody, clk2a antibody, clk2.L antibody, Clk2 antibody

Background: This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.,CLK2,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,CLK2

Molecular Weight: 17 kDa/59 kDa/60 kDa

Gene ID: 1196

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process