CLCN1 antibody (AA 779-988)

Catalog No. ABIN6138661

Product Details anti-CLCN1 Antibody

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Binding Specificity: AA 779-988

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ARPTKKKTTQ DSTDLVDNMS PEEIEAWEQE QLSQPVCFDS CCIDQSPFQL VEQTTLHKTH TLFSLLGLHL AYVTSMGKLR GVLALEELQK AIEGHTKSGV QLRPPLASFR NTTSTRKSTG APPSSAENWN LPEDRPGATG TGDVIAASPE TPVPSPSPEP PLSLAPGKVE GELEELELVE SPGLEEELAD ILQGPSLRST DEEDEDELIL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 779-988 of human CLCN1 (NP_000074.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLCN1

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Alternative Name: CLCN1 (CLCN1 Products)

Synonyms: CLCN1 antibody, si:dkey-14o18.5 antibody, Clc-1 antibody, Clc1 antibody, SMCC1 antibody, adr antibody, mto antibody, myotonia antibody, nmf355 antibody, SMCC antibody, CLC1 antibody, chloride voltage-gated channel 1 antibody, chloride channel, voltage-sensitive 1a antibody, chloride channel protein 1 antibody, chloride channel, voltage-sensitive 1 antibody, CLCN1 antibody, clcn1a antibody, LOC100550479 antibody, LOC703944 antibody, Clcn1 antibody

Background: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.,CLCN1,CLC1,Signal Transduction,Endocrine & Metabolism,Neuroscience,CLCN1

Molecular Weight: 108 kDa

Gene ID: 1180

UniProt: P35523