CHRM5 antibody (AA 230-430)

Catalog No. ABIN6138567

Product Details anti-CHRM5 Antibody

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Binding Specificity: AA 230-430

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LQGSDSVTKA EKRKPAHRAL FRSCLRCPRP TLAQRERNQA SWSSSRRSTS TTGKPSQATG PSANWAKAEQ LTTCSSYPSS EDEDKPATDP VLQVVYKSQG KESPGEEFSA EETEETFVKA ETEKSDYDTP NYLLSPAAAH RPKSQKCVAY KFRLVVKADG NQETNNGCHK VKIMPCPFPV AKEPSTKGLN PNPSHQMTKR K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-430 of human CHRM5 (NP_036257.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRM5

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Alternative Name: CHRM5 (CHRM5 Products)

Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown, however, stimulation of this receptor is known to increase cyclic AMP levels.,CHRM5,HM5,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRM5

Molecular Weight: 60 kDa

Gene ID: 1133

UniProt: P08912

Pathways: Synaptic Membrane