CHD4 antibody (AA 1520-1690)

Catalog No. ABIN6138512

Product Details anti-CHD4 Antibody

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Binding Specificity: AA 1520-1690

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: ELAEVEENKK MSQPGSPSPK TPTPSTPGDT QPNTPAPVPP AEDGIKIEEN SLKEEESIEG EKEVKSTAPE TAIECTQAPA PASEDEKVVV EPPEGEEKVE KAEVKERTEE PMETEPKGAA DVEKVEEKSA IDLTPIVVED KEEKKEEEEK KEVMLQNGET PKDLNDEKQK K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_001264.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHD4

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Alternative Name: CHD4 (CHD4 Products)

Synonyms: CHD4 antibody, im:7143343 antibody, si:ch211-51m24.3 antibody, si:ch211-57k11.10 antibody, wu:fb44b12 antibody, wu:fd12d03 antibody, MGC145363 antibody, Mi-2b antibody, Mi2-BETA antibody, Mi-2 antibody, 9530019N15Rik antibody, AA617397 antibody, BC005710 antibody, D6Ertd380e antibody, Mi-2beta antibody, mKIAA4075 antibody, b230399n07 antibody, chromodomain helicase DNA binding protein 4 antibody, chromodomain helicase DNA binding protein 4a antibody, chromodomain helicase DNA binding protein 4b antibody, chromodomain helicase DNA binding protein 4 L homeolog antibody, CHD4 antibody, chd4a antibody, chd4b antibody, chd4 antibody, Chd4 antibody, chd4.L antibody

Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.,CHD4,CHD-4,Mi-2b,Mi2-BETA,SIHIWES,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Immunology & Inflammation,CHD4

Molecular Weight: 218 kDa/220 kDa

Gene ID: 1108

UniProt: Q14839