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CFTR antibody (AA 1161-1480)
CFTR
Reactivity: Human
IF, WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CFTR Antibody
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Target
See all CFTR Antibodies
CFTR
(Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
Binding Specificity
All epitopes for CFTR antibodies
AA 1161-1480
Reactivity
All reactivities for CFTR antibodies
Human
Host
All hosts for CFTR antibodies
Rabbit
Clonality
All clonalities for CFTR antibodies
Polyclonal
Conjugate
All conjugates for CFTR antibodies
This CFTR antibody is un-conjugated
Application
All applications for CFTR antibodies
Immunofluorescence (IF), Western Blotting (WB)
Sequence
SRVFKFIDMP TEGKPTKSTK PYKNGQLSKV MIIENSHVKK DDIWPSGGQM TVKDLTAKYT EGGNAILENI SFSISPGQRV GLLGRTGSGK STLLSAFLRL LNTEGEIQID GVSWDSITLQ QWRKAFGVIP QKVFIFSGTF RKNLDPYEQW SDQEIWKVAD EVGLRSVIEQ FPGKLDFVLV DGGCVLSHGH KQLMCLARSV LSKAKILLLD EPSAHLDPVT YQIIRRTLKQ AFADCTVILC EHRIEAMLEC QQFLVIEENK VRQYDSIQKL LNERSLFRQA ISPSDRVKLF PHRNSSKCKS KPQIAALKEE TEEEVQDTRL
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1161-1480 of human CFTR (NP_000483.3).
Isotype
IgG
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Discover our top product CFTR Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CFTR
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Target
CFTR
(Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
Alternative Name
CFTR (CFTR Products )
Synonyms
ABC35 antibody, ABCC7 antibody, CF antibody, CFTR/MRP antibody, MRP7 antibody, TNR-CFTR antibody, dJ760C5.1 antibody, CFTR antibody, AW495489 antibody, Abcc7 antibody, RGD1561193 antibody, abc35 antibody, abcc7 antibody, cftr/mrp antibody, mrp7 antibody, tnr-cftr antibody, xcftr antibody, si:dkey-270i2.2 antibody, cystic fibrosis transmembrane conductance regulator antibody, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) antibody, CFTR antibody, cftr-A antibody, Cftr antibody, cftr antibody
Background
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.,CFTR,ABC35,ABCC7,CF,CFTR/MRP,MRP7,TNR-CFTR,dJ760C5.1,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,CFTR
Molecular Weight
69 kDa/161 kDa/168 kDa
Gene ID
1080
UniProt
P13569
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