CFP antibody (AA 190-469)

Catalog No. ABIN6138467

Product Details anti-CFP Antibody

Target: CFP (Complement Factor P (CFP))

Binding Specificity: AA 190-469

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: CPTHGAWATW GPWTPCSASC HGGPHEPKET RSRKCSAPEP SQKPPGKPCP GLAYEQRRCT GLPPCPVAGG WGPWGPVSPC PVTCGLGQTM EQRTCNHPVP QHGGPFCAGD ATRTHICNTA VPCPVDGEWD SWGEWSPCIR RNMKSISCQE IPGQQSRGRT CRGRKFDGHR CAGQQQDIRH CYSIQHCPLK GSWSEWSTWG LCMPPCGPNP TRARQRLCTP LLPKYPPTVS MVEGQGEKNV TFWGRPLPRC EELQGQKLVV EEKRPCLHVP ACKDPEEEEL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-469 of human CFP (NP_001138724.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CFP

Target: CFP (Complement Factor P (CFP))

Alternative Name: CFP (CFP Products)

Synonyms: BFD antibody, PFC antibody, PFD antibody, PROPERDIN antibody, BCFG antibody, Pfc antibody, Properdin antibody, complement factor properdin antibody, CFP antibody, Cfp antibody

Background: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.,CFP,BFD,PFC,PFD,PROPERDIN,properdin,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFP

Molecular Weight: 51 kDa

Gene ID: 5199

UniProt: P27918

Pathways: Complement System