Adipsin antibody (AA 26-253)

Catalog No. ABIN6138448

Product Details anti-Adipsin Antibody

Target: Adipsin (CFD) (Complement Factor D (CFD))

Binding Specificity: AA 26-253

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adipsin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ILGGREAEAH ARPYMASVQL NGAHLCGGVL VAEQWVLSAA HCLEDAADGK VQVLLGAHSL SQPEPSKRLY DVLRAVPHPD SQPDTIDHDL LLLQLSEKAT LGPAVRPLPW QRVDRDVAPG TLCDVAGWGI VNHAGRRPDS LQHVLLPVLD RATCNRRTHH DGAITERLMC AESNRRDSCK GDSGGPLVCG GVLEGVVTSG SRVCGNRKKP GIYTRVASYA AWIDSVLA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-253 of human CFD (NP_001919.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Adipsin

Target: Adipsin (CFD) (Complement Factor D (CFD))

Alternative Name: CFD (CFD Products)

Background: This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.,CFD,ADIPSIN,ADN,DF,PFD,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFD

Molecular Weight: 27 kDa

Gene ID: 1675

UniProt: P00746

Pathways: Complement System