CEMIP antibody (AA 180-420)

Catalog No. ABIN6138403

Product Details anti-CEMIP Antibody

Target: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Binding Specificity: AA 180-420

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEMIP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FERSWGHRGV IVHVIDPKSG TVIHSDRFDT YRSKKESERL VQYLNAVPDG RILSVAVNDE GSRNLDDMAR KAMTKLGSKH FLHLGFRHPW SFLTVKGNPS SSVEDHIEYH GHRGSAAARV FKLFQTEHGE YFNVSLSSEW VQDVEWTEWF DHDKVSQTKG GEKISDLWKA HPGKICNRPI DIQATTMDGV NLSTEVVYKK GQDYRFACYD RGRACRSYRV RFLCGKPVRP KLTVTIDTNV N

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-420 of human CEMIP (NP_061159.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CEMIP

Target: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Alternative Name: CEMIP (CEMIP Products)

Synonyms: CCSP1 antibody, TMEM2L antibody, 3110012M15Rik antibody, mKIAA1412 antibody, 12H19.01.T7 antibody, 6330404C01Rik antibody, AY007814 antibody, Kiaa1199 antibody, KIAA1199 antibody, cell migration inducing hyaluronan binding protein antibody, transmembrane protein 2 antibody, cell migration inducing protein, hyaluronan binding antibody, CEMIP antibody, Tmem2 antibody, TMEM2 antibody, Cemip antibody

Background: Mediates depolymerization of hyaluronic acid (HA via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT, and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.,CEMIP,CCSP1,HYBID,KIAA1199,TMEM2L,Cancer,Tumor suppressors,Neuroscience,CEMIP

Molecular Weight: 110 kDa/152 kDa

Gene ID: 57214

UniProt: Q8WUJ3