CELF1 antibody (AA 108-483)

Catalog No. ABIN6138399

Product Details anti-CELF1 Antibody

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Binding Specificity: AA 108-483

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: RKLFIGMISK KCTENDIRVM FSSFGQIEEC RILRGPDGLS RGCAFVTFTT RAMAQTAIKA MHQAQTMEGC SSPMVVKFAD TQKDKEQKRM AQQLQQQMQQ ISAASVWGNL AGLNTLGPQY LALLQQTASS GNLNTLSSLH PMGGLNAMQL QNLAALAAAA SAAQNTPSGT NALTTSSSPL SVLTSSAGSS PSSSSSNSVN PIASLGALQT LAGATAGLNV GSLAGMAALN GGLGSSGLSN GTGSTMEALT QAYSGIQQYA AAALPTLYNQ NLLTQQSIGA AGSQKEGPEG ANLFIYHLPQ EFGDQDLLQM FMPFGNVVSA KVFIDKQTNL SKCFGFVSYD NPVSAQAAIQ SMNGFQIGMK RLKVQLKRSK NDSKPY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 108-483 of human CELF1 (NP_941989.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CELF1

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Alternative Name: CELF1 (CELF1 Products)

Background: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.,CELF1,BRUNOL2,CUG-BP,CUGBP,CUGBP1,EDEN-BP,NAB50,NAPOR,hNab50,Epigenetics & Nuclear Signaling,RNA Binding,Neuroscience,Neurodegenerative Diseases,CELF1

Molecular Weight: 50 kDa/51 kDa/52 kDa/55 kDa

Gene ID: 10658

UniProt: Q92879

Pathways: Ribonucleoprotein Complex Subunit Organization