CD38 antibody (AA 46-300)

Catalog No. ABIN6138177

Product Details anti-CD38 Antibody

Target: CD38

Binding Specificity: AA 46-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD38 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: WRQQWSGPGT TKRFPETVLA RCVKYTEIHP EMRHVDCQSV WDAFKGAFIS KHPCNITEED YQPLMKLGTQ TVPCNKILLW SRIKDLAHQF TQVQRDMFTL EDTLLGYLAD DLTWCGEFNT SKINYQSCPD WRKDCSNNPV SVFWKTVSRR FAEAACDVVH VMLNGSRSKI FDKNSTFGSV EVHNLQPEKV QTLEAWVIHG GREDSRDLCQ DPTIKELESI ISKRNIQFSC KNIYRPDKFL QCVKNPEDSS CTSEI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 46-300 of human CD38 (NP_001766.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD38

Target: CD38

Abstract: CD38 Products

Synonyms: T10 antibody, Cd38-rs1 antibody, cd38 antibody, ADPRC 1 antibody, cADPr hydrolase 1 antibody, CD38 molecule antibody, CD38 antigen antibody, CD38 molecule L homeolog antibody, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 antibody, CD38 antibody, Cd38 antibody, cd38.L antibody

Background: The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.,CD38,ADPRC 1,ADPRC1,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD38

Molecular Weight: 13 kDa/34 kDa

Gene ID: 952

UniProt: P28907