CARS antibody (AA 469-748)

Catalog No. ABIN6137946

Product Details anti-CARS Antibody

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Binding Specificity: AA 469-748

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: ILRAPVDITG QFEKWGEEEA ELNKNFYDKK TAIHKALCDN VDTRTVMEEM RALVSQCNLY MAARKAVRKR PNQALLENIA LYLTHMLKIF GAVEEDSSLG FPVGGPGTSL SLEATVMPYL QVLSEFREGV RKIAREQKVP EILQLSDALR DNILPELGVR FEDHEGLPTV VKLVDRNTLL KEREEKRRVE EEKRKKKEEA ARRKQEQEAA KLAKMKIPPS EMFLSETDKY SKFDENGLPT HDMEGKELSK GQAKKLKKLF EAQEKLYKEY LQMAQNGSFQ

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 469-748 of human CARS (NP_001742.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CARS

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Alternative Name: CARS (CARS Products)

Background: This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.,CARS,CARS1,CYSRS,MGC:11246,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Nucleotide metabolism,CARS

Molecular Weight: 82 kDa/85 kDa/94 kDa

Gene ID: 833

UniProt: P49589