CARD10 antibody (AA 863-1032)

Catalog No. ABIN6137937

Product Details anti-CARD10 Antibody

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Binding Specificity: AA 863-1032

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: LLDLPSSRLD FQVCPAESLS GEELCPSSAP GAPKAQPATP GLGSRIRAIQ ESVGKKHCLL ELGARGVREL VQNEIYPIVI HVEVTEKNVR EVRGLLGRPG WRDSELLRQC RGSEQVLWGL PCSWVQVPAH EWGHAEELAK VVRGRILQEQ ARLVWVECGS SRGCPSSSEA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 863-1032 of human CARD10 (NP_055365.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CARD10

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Alternative Name: CARD10 (CARD10 Products)

Background: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB, see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008],CARD10,BIMP1,CARMA3,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD10

Molecular Weight: 82 kDa/115 kDa

Gene ID: 29775

UniProt: Q9BWT7

Pathways: S100 Proteins