CAPN10 antibody (AA 1-230)
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- Target See all CAPN10 Antibodies
- CAPN10 (Calpain 10 (CAPN10))
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Binding Specificity
- AA 1-230
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CAPN10 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MRAGRGATPA RELFRDAAFP AADSSLFCDL STPLAQFRED ITWRRPQEIC ATPRLFPDDP REGQVKQGLL GDCWFLCACA ALQKSRHLLD QVIPPGQPSW ADQEYRGSFT CRIWQFGRWV EVTTDDRLPC LAGRLCFSRC QREDVFWLPL LEKVYAKVHG SYEHLWAGQV ADALVDLTGG LAERWNLKGV AGSGGQQDRP GRWEHRTCRQ LLHLKDQCLI SCCVLSPRAG
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CAPN10 (NP_075571.1).
- Isotype
- IgG
- Top Product
- Discover our top product CAPN10 Primary Antibody
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- Application Notes
- WB,1:1000 - 1:4000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CAPN10 (Calpain 10 (CAPN10))
- Alternative Name
- CAPN10 (CAPN10 Products)
- Synonyms
- CAPN10 antibody, CANP10 antibody, NIDDM1 antibody, AW049679 antibody, Capn8 antibody, mKIAA1845 antibody, calpain 10 antibody, calpain 10 L homeolog antibody, CAPN10 antibody, capn10.L antibody, capn10 antibody, Capn10 antibody
- Background
- Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.,CAPN10,CANP10,NIDDM1,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Endocrine and metabolic diseases,Metabolic disorders,Neuroscience,Calcium Signaling,CAPN10
- Molecular Weight
- 15 kDa/29 kDa/49 kDa/57 kDa/60 kDa/74 kDa
- Gene ID
- 11132
- UniProt
- Q9HC96
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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