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CACNB4 antibody (AA 401-520)
CACNB4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CACNB4 Antibody
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Target
See all CACNB4 Antibodies
CACNB4
(Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
Binding Specificity
All epitopes for CACNB4 antibodies
AA 401-520
Reactivity
All reactivities for CACNB4 antibodies
Human
Host
All hosts for CACNB4 antibodies
Rabbit
Clonality
All clonalities for CACNB4 antibodies
Polyclonal
Conjugate
All conjugates for CACNB4 antibodies
This CACNB4 antibody is un-conjugated
Application
All applications for CACNB4 antibodies
Western Blotting (WB)
Sequence
ATHTTSSTPM TPLLGRNLGS TALSPYPTAI SGLQSQRMRH SNHSTENSPI ERRSLMTSDE NYHNERARKS RNRLSSSSQH SRDHYPLVEE DYPDSYQDTY KPHRNRGSPG GYSHDSRHRL
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 401-520 of human CACNB4 (NP_000717.2).
Isotype
IgG
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Discover our top product CACNB4 Primary Antibody
Alternatives
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anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (Middle Region) antibody
CACNB4
Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (AA 250-300) antibody
CACNB4
Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Zebrafish (Danio rerio), Guinea Pig, Pig, Xenopus laevis, Chicken
WB
Host: Rabbit
Polyclonal
unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (AA 361-410) antibody
CACNB4
Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse, Zebrafish (Danio rerio), Guinea Pig, Pig, Monkey, Bat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:1000 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CACNB4
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Target
CACNB4
(Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
Alternative Name
CACNB4 (CACNB4 Products )
Synonyms
CAB4 antibody, CACNLB4 antibody, EA5 antibody, EIG9 antibody, EJM antibody, EJM4 antibody, EJM6 antibody, 3110038O15Rik antibody, Cchb4 antibody, lethargic antibody, lh antibody, CACNB4 antibody, cacnb4.2 antibody, calcium voltage-gated channel auxiliary subunit beta 4 antibody, calcium channel, voltage-dependent, beta 4 subunit antibody, calcium channel, voltage-dependent, beta 4a subunit antibody, CACNB4 antibody, Cacnb4 antibody, cacnb4.1 antibody, cacnb4 antibody, cacnb4a antibody
Background
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene.,CACNB4,CAB4,CACNLB4,EA5,EIG9,EJM,EJM4,EJM6,Signal Transduction,Neuroscience,Calcium Signaling,CACNB4
Molecular Weight
51 kDa/54 kDa/56 kDa/58 kDa
Gene ID
785
UniProt
O00305
Pathways
cAMP Metabolic Process , Skeletal Muscle Fiber Development
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