BRD4 antibody (AA 1100-1200)

Catalog No. ABIN6137653

Product Details anti-BRD4 Antibody

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Binding Specificity: AA 1100-1200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1100-1200 of human BRD4 (NP_490597.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Alternative Name: BRD4 (BRD4 Products)

Synonyms: brd4-b antibody, BRD4 antibody, fb18g03 antibody, wu:fb18g03 antibody, CAP antibody, HUNK1 antibody, HUNKI antibody, MCAP antibody, Brd5 antibody, WI-11513 antibody, bromodomain containing 4 L homeolog antibody, bromodomain containing 4 antibody, bromodomain-containing protein 4 antibody, brd4.L antibody, BRD4 antibody, brd4 antibody, LOC100409351 antibody, Brd4 antibody

Background: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.,BRD4,CAP,HUNK1,HUNKI,MCAP,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,BRD4

Molecular Weight: 80 kDa/88 kDa/152 kDa

Gene ID: 23476

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome